tiopronin [Adjuvant]

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Ontology CARD's Antibiotic Resistance Ontology
Accession ARO:3007303
DefinitionTiopronin is a drug used to prevent and manage kidney stones in cystinuria patients. It has shown inhibitory activity against various metallo-beta-lactamases.
SMILESCC(S)C(=O)NCC(=O)O
PubChem5483
ChEBI32229
CAS1953-02-2
ChEMBLCHEMBL1314
Classification5 ontology terms | Show
Parent Term(s)4 ontology terms | Show
+ is_small_molecule_inhibitor_of NDM-1
+ is_small_molecule_inhibitor_of IMP-7
+ is_small_molecule_inhibitor_of VIM-1
+ unclassified metallo-beta-lactamase inhibitor
Publications

González-Bello C, et al. 2020. J Med Chem 63(5):1859-1881 β-Lactamase Inhibitors To Restore the Efficacy of Antibiotics against Superbugs. (PMID 31663735)

Curator Acknowledgements
Curator Description Most Recent Edit