avibactam [Adjuvant]

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Accession ARO:3000588
Synonym(s)NXL-104
DefinitionSer beta-lactamase inhibitor targeting class A, class C, and some class D enzymes.
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
Publications

Stachyra T, et al. 2010. Antimicrob Agents Chemother 54(12): 5132-5138. Mechanistic studies of the inactivation of TEM-1 and P99 by NXL104, a novel non-beta-lactam beta-lactamase inhibitor. (PMID 20921316)

Hidalgo JA, et al. 2016. Drug Des Devel Ther 10:2379-86 Ceftazidime/avibactam: a novel cephalosporin/nonbeta-lactam beta-lactamase inhibitor for the treatment of complicated urinary tract infections and complicated intra-abdominal infections. (PMID 27528799)

Torrens G, et al. 2016. Antimicrob. Agents Chemother. : Activity of ceftazidime-avibactam against clinical and isogenic laboratory Pseudomonas aeruginosa isolates expressing combinations of most relevant β-lactam resistance mechanisms. (PMID 27480848)