AcrAD-TolC

Accession ARO:3004082
DefinitionAcrAD-TolC efflux pump system in E. coli from the resistance-nodulation-division family, was shown to participate in the efflux of aminoglycosides.
AMR Gene Familyresistance-nodulation-cell division (RND) antibiotic efflux pump
Drug Classtetracycline antibiotic, antibacterial free fatty acids, aminoglycoside antibiotic, penam, glycylcycline, phenicol antibiotic, diaminopyrimidine antibiotic, carbapenem, monobactam, fluoroquinolone antibiotic, acridine dye, macrolide antibiotic, triclosan, aminocoumarin antibiotic
Resistance Mechanismantibiotic efflux
Efflux Componentefflux pump complex or subunit conferring antibiotic resistance
Classification22 ontology terms | Show
Parent Term(s)1 ontology terms | Show
Sub-Term(s)
3 ontology terms | Show
Publications

Rosenberg EY, et al. 2000. J Bacteriol 182(6): 1754-1756. AcrD of Escherichia coli is an aminoglycoside efflux pump. (PMID 10692383)

Poole K. 2004. Clin Microbiol Infect 10(1): 12-26. Efflux-mediated multiresistance in Gram-negative bacteria. (PMID 14706082)