Enterobacter cloacae rob

Accession ARO:3004108
Synonym(s)robA
CARD Short NameEclo_rob
Definitionrob is a positive regulator for the acrAB efflux genes, and is structurally similar to SoxS and MarA.
AMR Gene Familyresistance-nodulation-cell division (RND) antibiotic efflux pump
Drug Classtetracycline antibiotic, penicillin beta-lactam, cephalosporin, disinfecting agents and antiseptics, phenicol antibiotic, rifamycin antibiotic, glycylcycline, fluoroquinolone antibiotic, macrolide antibiotic
Resistance Mechanismantibiotic efflux
Efflux Componentefflux pump complex or subunit conferring antibiotic resistance
Efflux Regulatorprotein(s) and two-component regulatory system modulating antibiotic efflux
Classification28 ontology terms | Show
Parent Term(s)4 ontology terms | Show
+ confers_resistance_to_antibiotic erythromycin [Antibiotic]
+ confers_resistance_to_antibiotic tetracycline [Antibiotic]
+ confers_resistance_to_antibiotic telithromycin [Antibiotic]
+ rob
Publications

Perez A, et al. 2012. Antimicrob Agents Chemother 56(12): 6256-6266. Effect of transcriptional activators SoxS, RobA, and RamA on expression of multidrug efflux pump AcrAB-TolC in Enterobacter cloacae. (PMID 23006750)

Private model - RGI is not currently using this model.

Curator Acknowledgements
Curator Description Most Recent Edit