Enterobacter cloacae rob

Accession ARO:3004108
CARD Short NameEclo_rob
Definitionrob is a positive regulator for the acrAB efflux genes, and is structurally similar to SoxS and MarA.
AMR Gene Familyresistance-nodulation-cell division (RND) antibiotic efflux pump
Drug Classtetracycline antibiotic, penam, cephalosporin, phenicol antibiotic, rifamycin antibiotic, glycylcycline, disinfecting agents and antiseptics, fluoroquinolone antibiotic, macrolide antibiotic
Resistance Mechanismantibiotic efflux
Efflux Componentefflux pump complex or subunit conferring antibiotic resistance
Efflux Regulatorprotein(s) and two-component regulatory system modulating antibiotic efflux
Classification27 ontology terms | Show
Parent Term(s)4 ontology terms | Show
+ rob
+ confers_resistance_to_antibiotic erythromycin [Antibiotic]
+ confers_resistance_to_antibiotic tetracycline [Antibiotic]
+ confers_resistance_to_antibiotic telithromycin [Antibiotic]

Perez A, et al. 2012. Antimicrob Agents Chemother 56(12): 6256-6266. Effect of transcriptional activators SoxS, RobA, and RamA on expression of multidrug efflux pump AcrAB-TolC in Enterobacter cloacae. (PMID 23006750)

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