Ontology | CARD's Antibiotic Resistance Ontology |
Accession | ARO:3007298 |
Synonym(s) | VNRX-5236 |
Definition | Ledaborbactam is an experimental boronic acid beta-lactamase inhibitor that has shown been show to inhibitor several serine beta-lactamases. |
SMILES | CCC(=O)N[C@H]1Cc2cccc(C(=O)O)c2OB1O |
PubChem | 138455079 |
ChEMBL | CHEMBL5093566 |
Classification | 5 ontology terms | Show |
Parent Term(s) | 4 ontology terms | Show + is_small_molecule_inhibitor_of SHV-5 + is_small_molecule_inhibitor_of CTX-M-15 + is_small_molecule_inhibitor_of KPC-2 + boronic acid beta-lactamase inhibitor |
Publications | Chatwin CL, et al. 2021. Antimicrob Agents Chemother 65(8):e0055221 Microbiological Characterization of VNRX-5236, a Broad-Spectrum β-Lactamase Inhibitor for Rescue of the Orally Bioavailable Cephalosporin Ceftibuten as a Carbapenem-Sparing Agent against Strains of Enterobacterales Expressing Extended-Spectrum β-Lactamases and Serine Carbapenemases. (PMID 34001510) |
Curator | Description | Most Recent Edit |
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