ceftazidime [Antibiotic]

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Ontology CARD's Antibiotic Resistance Ontology
Accession ARO:0000060
Synonym(s)caftazidime CAZ Ceftazidim ceftazidima ceftazidimum Ceptaz Fortaz Pentacef Tazicef Tazidime
DefinitionCeftazidime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram-positive and Gram-negative bacteria. Unlike most third-generation agents, it is active against Pseudomonas aeruginosa, however it has weaker activity against Gram-positive microorganisms and is not used for such infections.
SMILESCC(C)(O/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)[O-])=C(C[n+]3ccccc3)CS[C@H]12)c1csc(N)n1)C(=O)O
PubChem5481173
ChEMBLCHEMBL44354
ChEBI3508
CAS72558-82-8
Drug Classcephalosporin
Classification4 ontology terms | Show
Parent Term(s)1 ontology terms | Show
Sub-Term(s)
262 ontology terms | Show
+ beta-lactam sensitive penicillin-binding protein targeted_by_antibiotic
+ CAM-1 confers_resistance_to_antibiotic
+ ACI-1 confers_resistance_to_antibiotic
+ Klebsiella pneumoniae KpnGH-TolC confers_resistance_to_antibiotic
+ MexAB-OprM confers_resistance_to_antibiotic
+ Burkholderia pseudomallei Omp38 confers_resistance_to_antibiotic
+ SHV-12 confers_resistance_to_antibiotic
+ CTX-M-15 confers_resistance_to_antibiotic
+ CTX-M-55 confers_resistance_to_antibiotic
+ CMY-42 confers_resistance_to_antibiotic
+ NDM-5 confers_resistance_to_antibiotic
+ OXA-2 confers_resistance_to_antibiotic
+ PDC-3 confers_resistance_to_antibiotic
+ PDC-5 confers_resistance_to_antibiotic
+ PDC-9 confers_resistance_to_antibiotic
+ PDC-10 confers_resistance_to_antibiotic
+ TMB-1 confers_resistance_to_antibiotic
+ TMB-2 confers_resistance_to_antibiotic
+ CTX-M-27 confers_resistance_to_antibiotic
+ CMY-2 confers_resistance_to_antibiotic
+ CTX-M-3 confers_resistance_to_antibiotic
+ SCO-1 confers_resistance_to_antibiotic
+ NDM-33 confers_resistance_to_antibiotic
+ Klebsiella pneumoniae OmpK35 confers_resistance_to_antibiotic
+ MAB confers_resistance_to_antibiotic
+ Escherichia coli AcrAB-TolC with AcrR mutation conferring resistance to ciprofloxacin, tetracycline, and ceftazidime confers_resistance_to_antibiotic
+ KPC-123 confers_resistance_to_antibiotic
+ VIM-63 confers_resistance_to_antibiotic
+ PAM-1 confers_resistance_to_antibiotic
+ PAM-2 confers_resistance_to_antibiotic
+ YRC-1 confers_resistance_to_antibiotic
+ KPC-95 confers_resistance_to_antibiotic
+ KPC-94 confers_resistance_to_antibiotic
+ KPC-86 confers_resistance_to_antibiotic
+ Klebsiella pneumoniae lamB with mutations conferring resistance to ceftazidime-avibactam confers_resistance_to_antibiotic
+ Klebsiella pneumoniae PBP3 mutants conferring resistance to ceftazidime-avibactam confers_resistance_to_antibiotic
+ Escherichia coli PBP3 mutants conferring resistance to beta-lactam antibiotics confers_resistance_to_antibiotic
+ KPC-96 confers_resistance_to_antibiotic
+ SSA confers_resistance_to_antibiotic
+ EBR-5 confers_resistance_to_antibiotic
+ KPC-100 confers_resistance_to_antibiotic
+ KPC-98 confers_resistance_to_antibiotic
+ KPC-97 confers_resistance_to_antibiotic
+ KPC-99 confers_resistance_to_antibiotic
+ ACC-1 confers_resistance_to_antibiotic
+ ACC-2 confers_resistance_to_antibiotic
+ ACC-4 confers_resistance_to_antibiotic
+ ACC-8 confers_resistance_to_antibiotic
+ ACC-7 confers_resistance_to_antibiotic
+ ACC-5 confers_resistance_to_antibiotic
+ ACC-3 confers_resistance_to_antibiotic
+ ACC-1d confers_resistance_to_antibiotic
+ ACC-1c confers_resistance_to_antibiotic
+ ACC-1b confers_resistance_to_antibiotic
+ ACC-1a confers_resistance_to_antibiotic
+ TEM-10 confers_resistance_to_antibiotic
+ TEM-101 confers_resistance_to_antibiotic
+ TEM-102 confers_resistance_to_antibiotic
+ TEM-104 confers_resistance_to_antibiotic
+ TEM-105 confers_resistance_to_antibiotic
+ TEM-106 confers_resistance_to_antibiotic
+ TEM-107 confers_resistance_to_antibiotic
+ TEM-108 confers_resistance_to_antibiotic
+ TEM-109 confers_resistance_to_antibiotic
+ TEM-121 confers_resistance_to_antibiotic
+ TEM-11 confers_resistance_to_antibiotic
+ TEM-110 confers_resistance_to_antibiotic
+ TEM-111 confers_resistance_to_antibiotic
+ TEM-112 confers_resistance_to_antibiotic
+ TEM-113 confers_resistance_to_antibiotic
+ TEM-114 confers_resistance_to_antibiotic
+ TEM-115 confers_resistance_to_antibiotic
+ TEM-116 confers_resistance_to_antibiotic
+ TEM-117 confers_resistance_to_antibiotic
+ TEM-118 confers_resistance_to_antibiotic
+ TEM-122 confers_resistance_to_antibiotic
+ TEM-12 confers_resistance_to_antibiotic
+ TEM-120 confers_resistance_to_antibiotic
+ TEM-123 confers_resistance_to_antibiotic
+ TEM-124 confers_resistance_to_antibiotic
+ TEM-125 confers_resistance_to_antibiotic
+ TEM-126 confers_resistance_to_antibiotic
+ TEM-127 confers_resistance_to_antibiotic
+ TEM-128 confers_resistance_to_antibiotic
+ TEM-129 confers_resistance_to_antibiotic
+ TEM-130 confers_resistance_to_antibiotic
+ TEM-131 confers_resistance_to_antibiotic
+ TEM-132 confers_resistance_to_antibiotic
+ TEM-133 confers_resistance_to_antibiotic
+ TEM-134 confers_resistance_to_antibiotic
+ TEM-136 confers_resistance_to_antibiotic
+ TEM-137 confers_resistance_to_antibiotic
+ TEM-138 confers_resistance_to_antibiotic
+ TEM-139 confers_resistance_to_antibiotic
+ TEM-141 confers_resistance_to_antibiotic
+ TEM-142 confers_resistance_to_antibiotic
+ TEM-143 confers_resistance_to_antibiotic
+ TEM-144 confers_resistance_to_antibiotic
+ TEM-145 confers_resistance_to_antibiotic
+ TEM-146 confers_resistance_to_antibiotic
+ TEM-147 confers_resistance_to_antibiotic
+ TEM-148 confers_resistance_to_antibiotic
+ TEM-149 confers_resistance_to_antibiotic
+ TEM-15 confers_resistance_to_antibiotic
+ TEM-150 confers_resistance_to_antibiotic
+ TEM-151 confers_resistance_to_antibiotic
+ TEM-152 confers_resistance_to_antibiotic
+ TEM-153 confers_resistance_to_antibiotic
+ TEM-154 confers_resistance_to_antibiotic
+ TEM-155 confers_resistance_to_antibiotic
+ TEM-156 confers_resistance_to_antibiotic
+ TEM-157 confers_resistance_to_antibiotic
+ TEM-158 confers_resistance_to_antibiotic
+ TEM-159 confers_resistance_to_antibiotic
+ TEM-16 confers_resistance_to_antibiotic
+ TEM-160 confers_resistance_to_antibiotic
+ TEM-162 confers_resistance_to_antibiotic
+ TEM-163 confers_resistance_to_antibiotic
+ TEM-164 confers_resistance_to_antibiotic
+ TEM-166 confers_resistance_to_antibiotic
+ TEM-167 confers_resistance_to_antibiotic
+ TEM-168 confers_resistance_to_antibiotic
+ TEM-169 confers_resistance_to_antibiotic
+ TEM-17 confers_resistance_to_antibiotic
+ TEM-171 confers_resistance_to_antibiotic
+ TEM-176 confers_resistance_to_antibiotic
+ TEM-177 confers_resistance_to_antibiotic
+ TEM-178 confers_resistance_to_antibiotic
+ TEM-181 confers_resistance_to_antibiotic
+ TEM-182 confers_resistance_to_antibiotic
+ TEM-183 confers_resistance_to_antibiotic
+ TEM-184 confers_resistance_to_antibiotic
+ TEM-185 confers_resistance_to_antibiotic
+ TEM-186 confers_resistance_to_antibiotic
+ TEM-187 confers_resistance_to_antibiotic
+ TEM-188 confers_resistance_to_antibiotic
+ TEM-189 confers_resistance_to_antibiotic
+ TEM-19 confers_resistance_to_antibiotic
+ TEM-190 confers_resistance_to_antibiotic
+ TEM-191 confers_resistance_to_antibiotic
+ TEM-192 confers_resistance_to_antibiotic
+ TEM-193 confers_resistance_to_antibiotic
+ TEM-194 confers_resistance_to_antibiotic
+ TEM-195 confers_resistance_to_antibiotic
+ TEM-196 confers_resistance_to_antibiotic
+ TEM-197 confers_resistance_to_antibiotic
+ TEM-198 confers_resistance_to_antibiotic
+ TEM-199 confers_resistance_to_antibiotic
+ TEM-2 confers_resistance_to_antibiotic
+ TEM-20 confers_resistance_to_antibiotic
+ TEM-201 confers_resistance_to_antibiotic
+ TEM-205 confers_resistance_to_antibiotic
+ TEM-206 confers_resistance_to_antibiotic
+ TEM-207 confers_resistance_to_antibiotic
+ TEM-208 confers_resistance_to_antibiotic
+ TEM-209 confers_resistance_to_antibiotic
+ TEM-21 confers_resistance_to_antibiotic
+ TEM-210 confers_resistance_to_antibiotic
+ TEM-211 confers_resistance_to_antibiotic
+ TEM-212 confers_resistance_to_antibiotic
+ TEM-213 confers_resistance_to_antibiotic
+ TEM-214 confers_resistance_to_antibiotic
+ TEM-215 confers_resistance_to_antibiotic
+ TEM-216 confers_resistance_to_antibiotic
+ TEM-217 confers_resistance_to_antibiotic
+ TEM-219 confers_resistance_to_antibiotic
+ TEM-22 confers_resistance_to_antibiotic
+ TEM-220 confers_resistance_to_antibiotic
+ TEM-224 confers_resistance_to_antibiotic
+ TEM-225 confers_resistance_to_antibiotic
+ TEM-226 confers_resistance_to_antibiotic
+ TEM-227 confers_resistance_to_antibiotic
+ TEM-228 confers_resistance_to_antibiotic
+ TEM-229 confers_resistance_to_antibiotic
+ TEM-230 confers_resistance_to_antibiotic
+ TEM-231 confers_resistance_to_antibiotic
+ TEM-232 confers_resistance_to_antibiotic
+ TEM-233 confers_resistance_to_antibiotic
+ TEM-234 confers_resistance_to_antibiotic
+ TEM-235 confers_resistance_to_antibiotic
+ TEM-236 confers_resistance_to_antibiotic
+ TEM-237 confers_resistance_to_antibiotic
+ TEM-238 confers_resistance_to_antibiotic
+ TEM-24 confers_resistance_to_antibiotic
+ TEM-240 confers_resistance_to_antibiotic
+ TEM-241 confers_resistance_to_antibiotic
+ TEM-242 confers_resistance_to_antibiotic
+ TEM-243 confers_resistance_to_antibiotic
+ TEM-244 confers_resistance_to_antibiotic
+ TEM-245 confers_resistance_to_antibiotic
+ TEM-246 confers_resistance_to_antibiotic
+ TEM-247 confers_resistance_to_antibiotic
+ TEM-26 confers_resistance_to_antibiotic
+ TEM-28 confers_resistance_to_antibiotic
+ TEM-29 confers_resistance_to_antibiotic
+ TEM-3 confers_resistance_to_antibiotic
+ TEM-31 confers_resistance_to_antibiotic
+ TEM-32 confers_resistance_to_antibiotic
+ TEM-33 confers_resistance_to_antibiotic
+ TEM-34 confers_resistance_to_antibiotic
+ TEM-35 confers_resistance_to_antibiotic
+ TEM-36 confers_resistance_to_antibiotic
+ TEM-37 confers_resistance_to_antibiotic
+ TEM-39 confers_resistance_to_antibiotic
+ TEM-4 confers_resistance_to_antibiotic
+ TEM-40 confers_resistance_to_antibiotic
+ TEM-42 confers_resistance_to_antibiotic
+ TEM-43 confers_resistance_to_antibiotic
+ TEM-45 confers_resistance_to_antibiotic
+ TEM-47 confers_resistance_to_antibiotic
+ TEM-48 confers_resistance_to_antibiotic
+ TEM-49 confers_resistance_to_antibiotic
+ TEM-5 confers_resistance_to_antibiotic
+ TEM-52 confers_resistance_to_antibiotic
+ TEM-53 confers_resistance_to_antibiotic
+ TEM-54 confers_resistance_to_antibiotic
+ TEM-55 confers_resistance_to_antibiotic
+ TEM-57 confers_resistance_to_antibiotic
+ TEM-58 confers_resistance_to_antibiotic
+ TEM-59 confers_resistance_to_antibiotic
+ TEM-6 confers_resistance_to_antibiotic
+ TEM-60 confers_resistance_to_antibiotic
+ TEM-63 confers_resistance_to_antibiotic
+ TEM-67 confers_resistance_to_antibiotic
+ TEM-68 confers_resistance_to_antibiotic
+ TEM-7 confers_resistance_to_antibiotic
+ TEM-70 confers_resistance_to_antibiotic
+ TEM-71 confers_resistance_to_antibiotic
+ TEM-72 confers_resistance_to_antibiotic
+ TEM-73 confers_resistance_to_antibiotic
+ TEM-75 confers_resistance_to_antibiotic
+ TEM-76 confers_resistance_to_antibiotic
+ TEM-78 confers_resistance_to_antibiotic
+ TEM-79 confers_resistance_to_antibiotic
+ TEM-8 confers_resistance_to_antibiotic
+ TEM-80 confers_resistance_to_antibiotic
+ TEM-81 confers_resistance_to_antibiotic
+ TEM-82 confers_resistance_to_antibiotic
+ TEM-83 confers_resistance_to_antibiotic
+ TEM-84 confers_resistance_to_antibiotic
+ TEM-85 confers_resistance_to_antibiotic
+ TEM-86 confers_resistance_to_antibiotic
+ TEM-87 confers_resistance_to_antibiotic
+ TEM-88 confers_resistance_to_antibiotic
+ TEM-89 confers_resistance_to_antibiotic
+ TEM-9 confers_resistance_to_antibiotic
+ TEM-90 confers_resistance_to_antibiotic
+ TEM-91 confers_resistance_to_antibiotic
+ TEM-92 confers_resistance_to_antibiotic
+ TEM-93 confers_resistance_to_antibiotic
+ TEM-94 confers_resistance_to_antibiotic
+ TEM-95 confers_resistance_to_antibiotic
+ TEM-96 confers_resistance_to_antibiotic
+ TEM-98 confers_resistance_to_antibiotic
+ TEM-99 confers_resistance_to_antibiotic
+ TEM-61 confers_resistance_to_antibiotic
+ KPC-134 confers_resistance_to_antibiotic
+ DYB-1 confers_resistance_to_antibiotic
+ ceftazidime-cloxacillin [Antibiotic] has_part
+ ceftazidime-clavulanic acid [Antibiotic+Adjuvant] has_part
+ ceftazidime-tazobactam [Antibiotic+Adjuvant] has_part
+ ceftazidime-avibactam [Antibiotic+Adjuvant] has_part
Publications

Neu HC and Labthavikul P. 1982. Antimicrob Agents Chemother 21(1): 11-18. Antibacterial activity and beta-lactamase stability of ceftazidime, an aminothiazolyl cephalosporin potentially active against Pseudomonas aeruginosa. (PMID 6805421)
Curator Acknowledgements
Curator Description Most Recent Edit