Accession | ARO:0000060 |
Synonym(s) | caftazidime CAZ Ceftazidim ceftazidima ceftazidimum Ceptaz Fortaz Pentacef Tazicef Tazidime |
Definition | Ceftazidime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram-positive and Gram-negative bacteria. Unlike most third-generation agents, it is active against Pseudomonas aeruginosa, however it has weaker activity against Gram-positive microorganisms and is not used for such infections. |
Drug Class | cephalosporin |
Classification | 4 ontology terms | Show |
Parent Term(s) | 1 ontology terms | Show + cephalosporin [Drug Class] |
Sub-Term(s) | 264 ontology terms | Show + beta-lactam sensitive penicillin-binding protein targeted_by_antibiotic + CAM-1 confers_resistance_to_antibiotic + ACI-1 confers_resistance_to_antibiotic + Klebsiella pneumoniae KpnGH-TolC confers_resistance_to_antibiotic + MexAB-OprM with CpxR regulator conferring resistance to ciprofloxacin, ceftazidime, and aztreonam confers_resistance_to_antibiotic + MexAB-OprM confers_resistance_to_antibiotic + MexAB-OprM with MexR mutations confers resistance to multiple antibiotics confers_resistance_to_antibiotic + Burkholderia pseudomallei Omp38 confers_resistance_to_antibiotic + SHV-12 confers_resistance_to_antibiotic + CTX-M-15 confers_resistance_to_antibiotic + CTX-M-55 confers_resistance_to_antibiotic + CMY-42 confers_resistance_to_antibiotic + NDM-5 confers_resistance_to_antibiotic + OXA-2 confers_resistance_to_antibiotic + PDC-3 confers_resistance_to_antibiotic + PDC-5 confers_resistance_to_antibiotic + PDC-9 confers_resistance_to_antibiotic + PDC-10 confers_resistance_to_antibiotic + TMB-1 confers_resistance_to_antibiotic + TMB-2 confers_resistance_to_antibiotic + MexAB-OprM with NalC mutations conferring resistance to aztreonam confers_resistance_to_antibiotic + MexAB-OprM with NalD mutations conferring resistance to multiple antibiotics confers_resistance_to_antibiotic + CTX-M-27 confers_resistance_to_antibiotic + CMY-2 confers_resistance_to_antibiotic + CTX-M-3 confers_resistance_to_antibiotic + SCO-1 confers_resistance_to_antibiotic + NDM-33 confers_resistance_to_antibiotic + Klebsiella pneumoniae OmpK35 confers_resistance_to_antibiotic + MAB confers_resistance_to_antibiotic + Escherichia coli AcrAB-TolC with AcrR mutation conferring resistance to ciprofloxacin, tetracycline, and ceftazidime confers_resistance_to_antibiotic + KPC-123 confers_resistance_to_antibiotic + VIM-63 confers_resistance_to_antibiotic + PAM-1 confers_resistance_to_antibiotic + PAM-2 confers_resistance_to_antibiotic + Yrc-1 confers_resistance_to_antibiotic + KPC-95 confers_resistance_to_antibiotic + KPC-94 confers_resistance_to_antibiotic + KPC-86 confers_resistance_to_antibiotic + Klebsiella pneumoniae lamB with mutations conferring resistance to ceftazidime-avibactam confers_resistance_to_antibiotic + Klebsiella pneumoniae PBP3 mutants conferring resistance to ceftazidime-avibactam confers_resistance_to_antibiotic + Escherichia coli PBP3 mutants conferring resistance to beta-lactam antibiotics confers_resistance_to_antibiotic + KPC-96 confers_resistance_to_antibiotic + SSA confers_resistance_to_antibiotic + EBR-5 confers_resistance_to_antibiotic + KPC-100 confers_resistance_to_antibiotic + KPC-98 confers_resistance_to_antibiotic + KPC-97 confers_resistance_to_antibiotic + KPC-99 confers_resistance_to_antibiotic + ACC-1 confers_resistance_to_antibiotic + ACC-2 confers_resistance_to_antibiotic + ACC-4 confers_resistance_to_antibiotic + ACC-8 confers_resistance_to_antibiotic + ACC-7 confers_resistance_to_antibiotic + ACC-5 confers_resistance_to_antibiotic + ACC-3 confers_resistance_to_antibiotic + ACC-1d confers_resistance_to_antibiotic + ACC-1c confers_resistance_to_antibiotic + ACC-1b confers_resistance_to_antibiotic + ACC-1a confers_resistance_to_antibiotic + TEM-10 confers_resistance_to_antibiotic + TEM-101 confers_resistance_to_antibiotic + TEM-102 confers_resistance_to_antibiotic + TEM-104 confers_resistance_to_antibiotic + TEM-105 confers_resistance_to_antibiotic + TEM-106 confers_resistance_to_antibiotic + TEM-107 confers_resistance_to_antibiotic + TEM-108 confers_resistance_to_antibiotic + TEM-109 confers_resistance_to_antibiotic + TEM-121 confers_resistance_to_antibiotic + TEM-11 confers_resistance_to_antibiotic + TEM-110 confers_resistance_to_antibiotic + TEM-111 confers_resistance_to_antibiotic + TEM-112 confers_resistance_to_antibiotic + TEM-113 confers_resistance_to_antibiotic + TEM-114 confers_resistance_to_antibiotic + TEM-115 confers_resistance_to_antibiotic + TEM-116 confers_resistance_to_antibiotic + TEM-117 confers_resistance_to_antibiotic + TEM-118 confers_resistance_to_antibiotic + TEM-122 confers_resistance_to_antibiotic + TEM-12 confers_resistance_to_antibiotic + TEM-120 confers_resistance_to_antibiotic + TEM-123 confers_resistance_to_antibiotic + TEM-124 confers_resistance_to_antibiotic + TEM-125 confers_resistance_to_antibiotic + TEM-126 confers_resistance_to_antibiotic + TEM-127 confers_resistance_to_antibiotic + TEM-128 confers_resistance_to_antibiotic + TEM-129 confers_resistance_to_antibiotic + TEM-130 confers_resistance_to_antibiotic + TEM-131 confers_resistance_to_antibiotic + TEM-132 confers_resistance_to_antibiotic + TEM-133 confers_resistance_to_antibiotic + TEM-134 confers_resistance_to_antibiotic + TEM-136 confers_resistance_to_antibiotic + TEM-137 confers_resistance_to_antibiotic + TEM-138 confers_resistance_to_antibiotic + TEM-139 confers_resistance_to_antibiotic + TEM-141 confers_resistance_to_antibiotic + TEM-142 confers_resistance_to_antibiotic + TEM-143 confers_resistance_to_antibiotic + TEM-144 confers_resistance_to_antibiotic + TEM-145 confers_resistance_to_antibiotic + TEM-146 confers_resistance_to_antibiotic + TEM-147 confers_resistance_to_antibiotic + TEM-148 confers_resistance_to_antibiotic + TEM-149 confers_resistance_to_antibiotic + TEM-15 confers_resistance_to_antibiotic + TEM-150 confers_resistance_to_antibiotic + TEM-151 confers_resistance_to_antibiotic + TEM-152 confers_resistance_to_antibiotic + TEM-153 confers_resistance_to_antibiotic + TEM-154 confers_resistance_to_antibiotic + TEM-155 confers_resistance_to_antibiotic + TEM-156 confers_resistance_to_antibiotic + TEM-157 confers_resistance_to_antibiotic + TEM-158 confers_resistance_to_antibiotic + TEM-159 confers_resistance_to_antibiotic + TEM-16 confers_resistance_to_antibiotic + TEM-160 confers_resistance_to_antibiotic + TEM-162 confers_resistance_to_antibiotic + TEM-163 confers_resistance_to_antibiotic + TEM-164 confers_resistance_to_antibiotic + TEM-166 confers_resistance_to_antibiotic + TEM-167 confers_resistance_to_antibiotic + TEM-168 confers_resistance_to_antibiotic + TEM-169 confers_resistance_to_antibiotic + TEM-17 confers_resistance_to_antibiotic + TEM-171 confers_resistance_to_antibiotic + TEM-176 confers_resistance_to_antibiotic + TEM-177 confers_resistance_to_antibiotic + TEM-178 confers_resistance_to_antibiotic + TEM-181 confers_resistance_to_antibiotic + TEM-182 confers_resistance_to_antibiotic + TEM-183 confers_resistance_to_antibiotic + TEM-184 confers_resistance_to_antibiotic + TEM-185 confers_resistance_to_antibiotic + TEM-186 confers_resistance_to_antibiotic + TEM-187 confers_resistance_to_antibiotic + TEM-188 confers_resistance_to_antibiotic + TEM-189 confers_resistance_to_antibiotic + TEM-19 confers_resistance_to_antibiotic + TEM-190 confers_resistance_to_antibiotic + TEM-191 confers_resistance_to_antibiotic + TEM-192 confers_resistance_to_antibiotic + TEM-193 confers_resistance_to_antibiotic + TEM-194 confers_resistance_to_antibiotic + TEM-195 confers_resistance_to_antibiotic + TEM-196 confers_resistance_to_antibiotic + TEM-197 confers_resistance_to_antibiotic + TEM-198 confers_resistance_to_antibiotic + TEM-199 confers_resistance_to_antibiotic + TEM-2 confers_resistance_to_antibiotic + TEM-20 confers_resistance_to_antibiotic + TEM-201 confers_resistance_to_antibiotic + TEM-205 confers_resistance_to_antibiotic + TEM-206 confers_resistance_to_antibiotic + TEM-207 confers_resistance_to_antibiotic + TEM-208 confers_resistance_to_antibiotic + TEM-209 confers_resistance_to_antibiotic + TEM-21 confers_resistance_to_antibiotic + TEM-210 confers_resistance_to_antibiotic + TEM-211 confers_resistance_to_antibiotic + TEM-212 confers_resistance_to_antibiotic + TEM-213 confers_resistance_to_antibiotic + TEM-214 confers_resistance_to_antibiotic + TEM-215 confers_resistance_to_antibiotic + TEM-216 confers_resistance_to_antibiotic + TEM-217 confers_resistance_to_antibiotic + TEM-219 confers_resistance_to_antibiotic + TEM-22 confers_resistance_to_antibiotic + TEM-220 confers_resistance_to_antibiotic + TEM-224 confers_resistance_to_antibiotic + TEM-225 confers_resistance_to_antibiotic + TEM-226 confers_resistance_to_antibiotic + TEM-227 confers_resistance_to_antibiotic + TEM-228 confers_resistance_to_antibiotic + TEM-229 confers_resistance_to_antibiotic + TEM-230 confers_resistance_to_antibiotic + TEM-231 confers_resistance_to_antibiotic + TEM-232 confers_resistance_to_antibiotic + TEM-233 confers_resistance_to_antibiotic + TEM-234 confers_resistance_to_antibiotic + TEM-235 confers_resistance_to_antibiotic + TEM-236 confers_resistance_to_antibiotic + TEM-237 confers_resistance_to_antibiotic + TEM-238 confers_resistance_to_antibiotic + TEM-24 confers_resistance_to_antibiotic + TEM-240 confers_resistance_to_antibiotic + TEM-241 confers_resistance_to_antibiotic + TEM-242 confers_resistance_to_antibiotic + TEM-243 confers_resistance_to_antibiotic + TEM-244 confers_resistance_to_antibiotic + TEM-245 confers_resistance_to_antibiotic + TEM-246 confers_resistance_to_antibiotic + TEM-247 confers_resistance_to_antibiotic + TEM-26 confers_resistance_to_antibiotic + TEM-28 confers_resistance_to_antibiotic + TEM-29 confers_resistance_to_antibiotic + TEM-3 confers_resistance_to_antibiotic + TEM-31 confers_resistance_to_antibiotic + TEM-32 confers_resistance_to_antibiotic + TEM-33 confers_resistance_to_antibiotic + TEM-34 confers_resistance_to_antibiotic + TEM-35 confers_resistance_to_antibiotic + TEM-36 confers_resistance_to_antibiotic + TEM-37 confers_resistance_to_antibiotic + TEM-39 confers_resistance_to_antibiotic + TEM-4 confers_resistance_to_antibiotic + TEM-40 confers_resistance_to_antibiotic + TEM-42 confers_resistance_to_antibiotic + TEM-43 confers_resistance_to_antibiotic + TEM-45 confers_resistance_to_antibiotic + TEM-47 confers_resistance_to_antibiotic + TEM-48 confers_resistance_to_antibiotic + TEM-49 confers_resistance_to_antibiotic + TEM-5 confers_resistance_to_antibiotic + TEM-52 confers_resistance_to_antibiotic + TEM-53 confers_resistance_to_antibiotic + TEM-54 confers_resistance_to_antibiotic + TEM-55 confers_resistance_to_antibiotic + TEM-57 confers_resistance_to_antibiotic + TEM-58 confers_resistance_to_antibiotic + TEM-59 confers_resistance_to_antibiotic + TEM-6 confers_resistance_to_antibiotic + TEM-60 confers_resistance_to_antibiotic + TEM-63 confers_resistance_to_antibiotic + TEM-67 confers_resistance_to_antibiotic + TEM-68 confers_resistance_to_antibiotic + TEM-7 confers_resistance_to_antibiotic + TEM-70 confers_resistance_to_antibiotic + TEM-71 confers_resistance_to_antibiotic + TEM-72 confers_resistance_to_antibiotic + TEM-73 confers_resistance_to_antibiotic + TEM-75 confers_resistance_to_antibiotic + TEM-76 confers_resistance_to_antibiotic + TEM-78 confers_resistance_to_antibiotic + TEM-79 confers_resistance_to_antibiotic + TEM-8 confers_resistance_to_antibiotic + TEM-80 confers_resistance_to_antibiotic + TEM-81 confers_resistance_to_antibiotic + TEM-82 confers_resistance_to_antibiotic + TEM-83 confers_resistance_to_antibiotic + TEM-84 confers_resistance_to_antibiotic + TEM-85 confers_resistance_to_antibiotic + TEM-86 confers_resistance_to_antibiotic + TEM-87 confers_resistance_to_antibiotic + TEM-88 confers_resistance_to_antibiotic + TEM-89 confers_resistance_to_antibiotic + TEM-9 confers_resistance_to_antibiotic + TEM-90 confers_resistance_to_antibiotic + TEM-91 confers_resistance_to_antibiotic + TEM-92 confers_resistance_to_antibiotic + TEM-93 confers_resistance_to_antibiotic + TEM-94 confers_resistance_to_antibiotic + TEM-95 confers_resistance_to_antibiotic + TEM-96 confers_resistance_to_antibiotic + TEM-98 confers_resistance_to_antibiotic + TEM-99 confers_resistance_to_antibiotic + TEM-61 confers_resistance_to_antibiotic + ceftazidime-cloxacillin [Antibiotic] has_part + ceftazidime-clavulanic acid [Antibiotic+Adjuvant] has_part + ceftazidime-tazobactam [Antibiotic+Adjuvant] has_part + ceftazidime-avibactam [Antibiotic+Adjuvant] has_part |
Publications | Neu HC and Labthavikul P. 1982. Antimicrob Agents Chemother 21(1): 11-18. Antibacterial activity and beta-lactamase stability of ceftazidime, an aminothiazolyl cephalosporin potentially active against Pseudomonas aeruginosa. (PMID 6805421) |