amoxicillin [Antibiotic]

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Accession ARO:0000064
Synonym(s)Amoxicilline AMX Amoxicilina D-Amoxicillin Amolin Amopenixin Amoxicillinum Amoxycillin Clamoxyl Moxal
DefinitionAmoxicillin is a moderate-spectrum, bacteriolytic, beta-lactam antibiotic used to treat bacterial infections caused by susceptible microorganisms. A derivative of penicillin, it has a wider range of treatment but remains relatively ineffective against Gram-negative bacteria. It is commonly taken with clavulanic acid, a beta-lactamase inhibitor. Like other beta-lactams, amoxicillin interferes with the synthesis of peptidoglycan.
Drug Classpenam
Classification3 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ penam [Drug Class]
Sub-Term(s)
12 ontology terms | Show
+ beta-lactam sensitive penicillin-binding protein targeted_by_antibiotic
+ Streptococcus pneumoniae PBP2x conferring resistance to amoxicillin confers_resistance_to_antibiotic
+ Streptococcus pneumoniae PBP2b conferring resistance to amoxicillin confers_resistance_to_antibiotic
+ Streptococcus pneumoniae PBP1a conferring resistance to amoxicillin confers_resistance_to_antibiotic
+ TEM-30 confers_resistance_to_antibiotic
+ TEM-1 confers_resistance_to_antibiotic
+ OXA-2 confers_resistance_to_antibiotic
+ OXA-1 confers_resistance_to_antibiotic
+ Moraxella catarrhalis M35 confers_resistance_to_antibiotic
+ blaF confers_resistance_to_antibiotic
+ ACI-1 confers_resistance_to_antibiotic
+ amoxicillin-clavulanic acid has_part
Publications

Salvo F, et al. 2009. Expert Opin Drug Saf 8(1): 111-118. Amoxicillin and amoxicillin plus clavulanate: a safety review. (PMID 19236222)