| Accession | ARO:0000064 |
| Synonym(s) | Amolin Amopenixin Amoxicilina Amoxicilline Amoxicillinum Amoxycillin AMX Clamoxyl D-Amoxicillin Moxal |
| Definition | Amoxicillin is a moderate-spectrum, bacteriolytic, beta-lactam antibiotic used to treat bacterial infections caused by susceptible microorganisms. A derivative of penicillin, it has a wider range of treatment but remains relatively ineffective against Gram-negative bacteria. It is commonly taken with clavulanic acid, a beta-lactamase inhibitor. Like other beta-lactams, amoxicillin interferes with the synthesis of peptidoglycan. |
| SMILES | CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(=O)O |
| PubChem | 33613 |
| ChEBI | 2676 |
| ChEMBL | CHEMBL1082 |
| CAS | 26787-78-0 |
| Drug Class | penicillin beta-lactam |
| Classification | 4 ontology terms | Show |
| Parent Term(s) | 1 ontology terms | Show |
| Sub-Term(s) | 33 ontology terms | Show + beta-lactam sensitive penicillin-binding protein targeted_by_antibiotic + Streptococcus pneumoniae PBP2x conferring resistance to amoxicillin confers_resistance_to_antibiotic + Streptococcus pneumoniae PBP2b conferring resistance to amoxicillin confers_resistance_to_antibiotic + Streptococcus pneumoniae PBP1a conferring resistance to amoxicillin confers_resistance_to_antibiotic + TEM-30 confers_resistance_to_antibiotic + TEM-1 confers_resistance_to_antibiotic + OXA-2 confers_resistance_to_antibiotic + OXA-1 confers_resistance_to_antibiotic + Moraxella catarrhalis M35 confers_resistance_to_antibiotic + blaF confers_resistance_to_antibiotic + ACI-1 confers_resistance_to_antibiotic + SCO-1 confers_resistance_to_antibiotic + Helicobacter pylori pbp3 conferring resistance to amoxicillin [Drug Class] confers_resistance_to_antibiotic + Helicobacter pylori pbp2 mutants conferring resistance to amoxicillin confers_resistance_to_antibiotic + Helicobacter pylori pbp1 mutants conferring resistance to amoxicillin confers_resistance_to_antibiotic + LAP-1 confers_resistance_to_antibiotic + LAP-2 confers_resistance_to_antibiotic + PRC-1 confers_resistance_to_antibiotic + MAB confers_resistance_to_antibiotic + blaC confers_resistance_to_antibiotic + KBL-1 confers_resistance_to_antibiotic + YRC-1 confers_resistance_to_antibiotic + VMB-1 confers_resistance_to_antibiotic + TUS-1 confers_resistance_to_antibiotic + MUS-1 confers_resistance_to_antibiotic + MUS-2 confers_resistance_to_antibiotic + SED-1 confers_resistance_to_antibiotic + SSA confers_resistance_to_antibiotic + Streptococcus pyogenes PBP2x conferring resistance to beta-lactam antibiotics confers_resistance_to_antibiotic + PSZ-1 confers_resistance_to_antibiotic + AMZ-1 confers_resistance_to_antibiotic + TEM-103 confers_resistance_to_antibiotic + amoxicillin-clavulanic acid [Antibiotic+Adjuvant] has_part |
| Publications | Salvo F, et al. 2009. Expert Opin Drug Saf 8(1): 111-118. Amoxicillin and amoxicillin plus clavulanate: a safety review. (PMID 19236222) |
| Curator | Description | Most Recent Edit |
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