Accession ARO:3000834
DefinitionPhoP is a direct repressor of the macAB efflux genes.
AMR Gene Familypmr phosphoethanolamine transferase, transmembrane protein conferring colistin resistance, ATP-binding cassette (ABC) antibiotic efflux pump
Drug Classpeptide antibiotic, macrolide antibiotic
Resistance Mechanismantibiotic target alteration, resistance by absence, antibiotic efflux
Efflux Componentefflux pump complex or subunit conferring antibiotic resistance
Efflux Regulatorprotein(s) and two-component regulatory system modulating antibiotic efflux
Classification32 ontology terms | Show
Parent Term(s)2 ontology terms | Show
2 ontology terms | Show

Lee JY, et al. 2014. Diagn Microbiol Infect Dis 78(3): 271-276. Mutations and expression of PmrAB and PhoPQ related with colistin resistance in Pseudomonas aeruginosa clinical isolates. (PMID 24412662)