| Accession | ARO:0000066 |
| Synonym(s) | Chlolincocin Chlorlincocin Cleocin CLI Clindamicina Clindamycine Clindamycinum Clinimycin Sobelin |
| Definition | Clindamycin is a lincosamide antibiotic that blocks A-site aminoacyl-tRNA binding. It is usually used to treat infections with anaerobic bacteria but can also be used to treat some protozoal diseases, such as malaria. |
| SMILES | N/A |
| PubChem | 446598 |
| Drug Class | lincosamide antibiotic |
| Classification | 2 ontology terms | Show |
| Parent Term(s) | 1 ontology terms | Show + lincosamide antibiotic [Drug Class] |
| Sub-Term(s) | 63 ontology terms | Show + antibiotic sensitive peptidyl transferase (23S rRNA) targeted_by_antibiotic + lsaA confers_resistance_to_antibiotic + ErmC confers_resistance_to_antibiotic + ErmE confers_resistance_to_antibiotic + ErmA confers_resistance_to_antibiotic + ErmB confers_resistance_to_antibiotic + Erm(37) confers_resistance_to_antibiotic + ErmD confers_resistance_to_antibiotic + ErmF confers_resistance_to_antibiotic + ErmG confers_resistance_to_antibiotic + ErmN confers_resistance_to_antibiotic + ErmQ confers_resistance_to_antibiotic + ErmR confers_resistance_to_antibiotic + ErmT confers_resistance_to_antibiotic + ErmX confers_resistance_to_antibiotic + Erm(33) confers_resistance_to_antibiotic + Erm(34) confers_resistance_to_antibiotic + Erm(38) confers_resistance_to_antibiotic + Erm(39) confers_resistance_to_antibiotic + Erm(41) confers_resistance_to_antibiotic + Erm(35) confers_resistance_to_antibiotic + Erm(36) confers_resistance_to_antibiotic + cfr(B) confers_resistance_to_antibiotic + LlmA 23S ribosomal RNA methyltransferase confers_resistance_to_antibiotic + cipA confers_resistance_to_antibiotic + cfrA confers_resistance_to_antibiotic + clbA confers_resistance_to_antibiotic + clbB confers_resistance_to_antibiotic + clbC confers_resistance_to_antibiotic + clcD confers_resistance_to_antibiotic + Escherichia coli 23S rRNA with mutation conferring resistance to clindamycin confers_resistance_to_antibiotic + Clostridioides difficile 23S rRNA with mutation conferring resistance to erythromycin and clindamycin confers_resistance_to_antibiotic + lmrC confers_resistance_to_antibiotic + lsaB confers_resistance_to_antibiotic + lsaC confers_resistance_to_antibiotic + salA confers_resistance_to_antibiotic + salB confers_resistance_to_antibiotic + salC confers_resistance_to_antibiotic + Erm(42) confers_resistance_to_antibiotic + Erm(43) confers_resistance_to_antibiotic + Erm(44)v confers_resistance_to_antibiotic + Erm(47) confers_resistance_to_antibiotic + Erm(48) confers_resistance_to_antibiotic + Erm(49) confers_resistance_to_antibiotic + Erm(50) confers_resistance_to_antibiotic + Erm(51) confers_resistance_to_antibiotic + Erm(52) confers_resistance_to_antibiotic + erm(40) confers_resistance_to_antibiotic + erm(45) confers_resistance_to_antibiotic + lnuB confers_resistance_to_antibiotic + lnuD confers_resistance_to_antibiotic + lnuF confers_resistance_to_antibiotic + lsaD confers_resistance_to_antibiotic + vga(E) Staphylococcus cohnii confers_resistance_to_antibiotic + vgaA confers_resistance_to_antibiotic + vgaALC confers_resistance_to_antibiotic + vgaC confers_resistance_to_antibiotic + vgaE confers_resistance_to_antibiotic + LnuH confers_resistance_to_antibiotic + Clostridioides difficile cplR confers_resistance_to_antibiotic + Clostridium perfringes cplR confers_resistance_to_antibiotic + Clostridium sporogenes cplR confers_resistance_to_antibiotic + erm(56) confers_resistance_to_antibiotic |
| Publications | Dunkle JA, et al. 2010. Proc Natl Acad Sci U S A 107(40): 17152-17157. Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action. (PMID 20876128) |
| Curator | Description | Most Recent Edit |
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