| Accession | ARO:3000158 |
| Synonym(s) | AZM |
| Definition | Azithromycin is a 15-membered macrolide and falls under the subclass of azalide. Like other macrolides, azithromycin binds bacterial ribosomes to inhibit protein synthesis. The nitrogen substitution at the C-9a position prevents its degradation. |
| Drug Class | macrolide antibiotic |
| Classification | 2 ontology terms | Show |
| Parent Term(s) | 1 ontology terms | Show + macrolide antibiotic [Drug Class] |
| Sub-Term(s) | 55 ontology terms | Show + EreB confers_resistance_to_antibiotic + MexAB-OprM confers_resistance_to_antibiotic + ErmC confers_resistance_to_antibiotic + ErmE confers_resistance_to_antibiotic + ErmA confers_resistance_to_antibiotic + ErmB confers_resistance_to_antibiotic + Erm(37) confers_resistance_to_antibiotic + ErmD confers_resistance_to_antibiotic + ErmF confers_resistance_to_antibiotic + ErmG confers_resistance_to_antibiotic + ErmN confers_resistance_to_antibiotic + ErmQ confers_resistance_to_antibiotic + ErmR confers_resistance_to_antibiotic + ErmT confers_resistance_to_antibiotic + ErmX confers_resistance_to_antibiotic + Erm(33) confers_resistance_to_antibiotic + Erm(34) confers_resistance_to_antibiotic + Erm(38) confers_resistance_to_antibiotic + Erm(39) confers_resistance_to_antibiotic + Erm(41) confers_resistance_to_antibiotic + Erm(35) confers_resistance_to_antibiotic + Erm(36) confers_resistance_to_antibiotic + mgtA confers_resistance_to_antibiotic + mphA confers_resistance_to_antibiotic + mphB confers_resistance_to_antibiotic + mphC confers_resistance_to_antibiotic + Klebsiella pneumoniae KpnGH-TolC confers_resistance_to_antibiotic + MexAB-OprM with MexR mutations confers resistance to multiple antibiotics confers_resistance_to_antibiotic + LpeAB confers_resistance_to_antibiotic + Mycobacterium intracellulare 23S rRNA with mutation conferring resistance to azithromycin confers_resistance_to_antibiotic + MtrCDE confers_resistance_to_antibiotic + Neisseria gonorrhoeae mtrR with mutation conferring resistance confers_resistance_to_antibiotic + Neisseria gonorrhoeae rpld confers_resistance_to_antibiotic + Neisseria gonorrhoeae 23S rRNA with mutation conferring resistance to azithromycin confers_resistance_to_antibiotic + Erm(47) confers_resistance_to_antibiotic + Erm(51) confers_resistance_to_antibiotic + ErmY confers_resistance_to_antibiotic + Chlamydia trachomatis 23S rRNA with mutation conferring resistance to macrolide antibiotics confers_resistance_to_antibiotic + Moraxella catarrhalis 23S rRNA with mutation conferring resistance to macrolide antibiotics confers_resistance_to_antibiotic + Mycoplasma genitalium 23S rRNA mutations confers resistance to fluoroquinolone and macrolide antibiotics confers_resistance_to_antibiotic + Mycoplasma hominis 23S rRNA with mutation conferring resistance to macrolide antibiotics confers_resistance_to_antibiotic + erm(46) confers_resistance_to_antibiotic + mphF confers_resistance_to_antibiotic + mphG confers_resistance_to_antibiotic + mphH confers_resistance_to_antibiotic + mphK confers_resistance_to_antibiotic + mphL confers_resistance_to_antibiotic + msr(G) confers_resistance_to_antibiotic + Mrx confers_resistance_to_antibiotic + lmrP confers_resistance_to_antibiotic + mef(B) confers_resistance_to_antibiotic + mef(F) confers_resistance_to_antibiotic + mreA confers_resistance_to_antibiotic + AmrAB-OprM confers_resistance_to_antibiotic + 50S ribosomal subunit P-site targeted_by_antibiotic |
| Publications | Williams JD. 1991. Eur J Clin Microbiol Infect Dis 10(10): 813-820. Spectrum of activity of azithromycin. (PMID 1662624) |
